The (4-1) Arizona Cardinals play host to the (2-3) Buffalo Bills in NFL Week 6. After opening at -250 ($1.40) in the moneyline odds we see that Arizona have drifted out slightly with their current odds trading between -225 ($1.44) up to -196 ($1.51). Buffalo are priced between +175 ($2.75) up to +185 ($2.85) after opening the week at +210 ($3.10). The point spread for this game has seen the sportbooks move the line in a half point from the opener with most outlets offering Arizona -4 Buffalo +4 and the over under total line is at O/U 44 points.
Those odds and lines have seen 54% of point spread wagers at a leading offshore sportsbook placed on the Cardinals to cover. Money line odds wagering has seen 61% of bets placed on the Bills and the over under totals action is split 50/50.
The Cardinals have averaged 273.2 total offensive yards per game compared with 351 for the Bills. Defensively Buffalo are ranked 31st in the league for average yards allowed (449.4) with Arizona 11th (334). In yards per play statistics the Cardinals have a differential of -.70 and the Bills are sporting a differential of -.80.
In NFL Odds Wagering Results Arizona has been the most profitable team in the league, showing +$773 (closing) and +$700 (opening) for $100 bets each week. Their 3-2 record against the closing spread is also showing a modest profit of +$85 while against the over under bet they are 1-4. Taking a look at Buffalo's wagering results thus far, they are 4-1 in over under betting, 2-3 (-$110) against the closing point spread and they are -$168 against the moneyline odds.
The Last Time they Played - was back in 2008 when the Arizona Cardinals prevailed 41-17 as -134 ($1.75) home favorites, covering the point spread of -2 while the total went well over the closer of O/U 44.5.
TheFootballLines.com's Verdict - The Cardinals are missing their top two rushers and with John Skelton likely to be available it could make things interesting. From a wagering perspective our numbers do see some value here and we have a point spread play. You can get our pick below or via one of our picks packages.